Some of the major times when humans are tested are through the constant fires of change and uncertainty. In short, we cannot improve ourselves without change.
As it happens, last week their son had to have a biopsy to test for recurrence of cancer he was treated for several years ago. They were worried as the test itself carried significant risk, due to the location of the tissue to be biopsied, so I went to sit and pray with them at the hospital while it was done. Today they await the results.